After a slow start at Springfield on Saturday, the Lions booted three unanswered goals in the second term to set up the 9.8 (62) to 4.9 (33) win.
It marked a perfect milestone for premiership captain Bre Koenen, who became just the third AFLW player to reach 100 games.
Koenen joined Lions teammate Ally Anderson and Adelaide star Ebony Marinoff in the 100 club.
Brisbane finish off strongly in warm conditions to turn the result into a percentage-booster, with a three-goals-to-one final term.
An energetic small forward, Hodder still put damage on the scoreboard, but also caused havoc up the field and had two direct goal assists.
The 25-year-old kicked a stunning goal in the second quarter after pulling down a strong mark.
Hodder finished with 24 possessions and laid six tackles, backing up a best-on-ground performance in the Lions' commanding QClash win over Gold Coast last week.
Dakota Davidson, Poppy Boltz and Orla O'Dwyer were also dangerous up forward, kicking two goals each
Brisbane's fourth-straight win keeps the Lions in touch with the top-four, giving them a chance of securing a double chance.
Perennial contenders, the Lions appeared capable of missing finals after they slumped to 2-3 following a crushing defeat to rampaging reigning premiers North Melbourne.
Luckless Port youngster Piper Window was concussed in her first game back from an ankle injury.
Window suffered a nasty knock when contesting the ball and was ruled out of the match at halftime by medicos.
Ashleigh Woodland was Port's best with 24 disposals, while Gemma Houghton was their only multiple goal-kicker with two.
Surprise preliminary finalists last year, Port sit two games and percentage outside of the top-eight with just three rounds remaining in the season.
Port's finals aspirations will go on the line next Friday night when they host second-placed Hawthorn at Alberton.
Brisbane will travel for their next clash, facing struggling Essendon at Windy Hill on Sunday.
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