Polling places will open at 8am tomorrow, and close at 6pm.
Counting will start immediately following the close of polls, with running tallies from the Australian Electoral Commission expected to be made public soon after.
But the AEC says it will not declare a result on election night.
While its sometime possible to make a prediction based on the virtual tally on election night, it could take days or weeks for the AEC to fully complete its by-election duties and due diligence before a result is officially declared.
SportsBet has 1.33 odds on One Nation Candidate David Farley being the successful candidate, with 3.30 odds assigned to an Independent - most likely Michelle Milthorpe - being the next local member.
The Liberals and Nationals come in a distant third and fourth, with odds of 19 and 51 respectively.
Today is the last day for early voting, available to those who will be outside the electorate tomorrow or unable to get to a polling place.
The Deniliquin early voting centre is located at the Deniliquin Army Cadets Hall in Victoria St, north Deniliquin, and open today from 8.30am to 6pm.
Tomorrow, you can cast your vote at any of the following locations: Blighty Public School; Deniliquin Army Cadet Hall; Deniliquin High School; Edward Public School; Mathoura Visitor Business Centre; Moulamein Public School; Tooleybuc Central School; Wakool Burraboi Public School.